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Mutant IDH1 inhibitor

CAS No. 1429180-08-4

Mutant IDH1 inhibitor( —— )

Catalog No. M23590 CAS No. 1429180-08-4

Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	151	In Stock
10MG	259	In Stock
25MG	437	In Stock
50MG	624	In Stock
100MG	888	In Stock
500MG	1773	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Mutant IDH1 inhibitor
Note

Research use only, not for human use.
Brief Description

Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
Description

Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
In Vitro

Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

mutant IDH1 R132H
Research Area

——
Indication

——

Chemical Information

CAS Number

1429180-08-4
Formula Weight

466.58
Molecular Formula

C25H34N6O3
Purity

>98% (HPLC)
Solubility

DMSO:30 mg/mL (64.3 mM)
SMILES

CC(C)[C@@H](COC1=O)N1c1nc(N[C@@H](C)c2ccc(CN(CC3)CCN3C(C)=O)cc2)ncc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404

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